Prostaglandin E2 selectively increases interferon gamma receptor expression on human CD8+ lymphocytes.
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چکیده
منابع مشابه
Prostaglandin E2 selectively increases interferon gamma receptor expression on human CD8+ lymphocytes.
We previously reported that prostaglandin E2 (PGE2) at a physiologic concentration (10(-8) M) and interferon gamma (IFN gamma), acting sequentially, were required for the differentiation of suppressor cells in mitogen-stimulated cultures. The present study was designed to test whether PGE2 might mediate IFN gamma-dependent effects on CD8+ cells by altering the number and/or affinity of their IF...
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ژورنال
عنوان ژورنال: Journal of Clinical Investigation
سال: 1989
ISSN: 0021-9738
DOI: 10.1172/jci114035